To understand the benefits of synthetic peptide hydrogel, it is important to understand what it is and how it is used. Scientific advancements in cell culture capability allows now for the creation of bespoke products by companies such as Manchester Biogel and a huge leap in cell culture abilities.
How they work
Synthetic peptide hydrogels are a completely reproducible chemically defined peptide hydrogel, giving the ability to create a 2D or 3D scaffold that is biologically relevant and formulated to a cell’s needs. They have the mechanical and chemical functionalities capable of mimicking native cellular microenvironments to allow the growth of any cell type.
These hydrogels offer a biocompatible and completely animal and disease-free hydrogel that can be replicated with no batch-to-batch variation in a convenient format for users. Fridge storage and ready to use formats make them an ideal choice as a cell culture scaffold.
When used alongside PeptiSols®, you are able to achieve multiple desired mechanical strengths, which ensure the properties, and stability of the hydrogel are maintained. They offer excellent biocompatibility and excellent injectability and are able to provide extracellular matrix-mimicking conditions and opportunities for biomedical applications such as wound healing and tissue engineering that is easily replicated.
Where and how are synthetic peptide hydrogels used?
These hydrogels are supplied for use in both 2D and 3D cell culture, bio printing, drug discovery and tissue regeneration. The use of synthetic peptide hydrogels has allowed many advances in medical sciences to create and test the efficacy of drug treatments.
They have enabled greater test capability without the need to test on animals and the ability to mimic accurately the behaviour of cells over both time and exposure to medication. Synthetic peptide hydrogels provide a temporary platform to enable regeneration of new tissue and restoration of injured tissue, the synthetic structure makes it easy to replicate and therefore ensure accurate results time and again for both testing and reconstruction use.
The benefit of synthetic peptide hydrogel
Synthetic peptide hydrogels are regularly replacing natural hydrogels as they offer a low cost, fully reproducible and consistent base for your cell culture requirements. Using a controllable synthetic hydrogel offers a long shelf life and reduced cost. A high water absorbing capacity and high gel strength make them suitable for a range of chemical functions that require a need to mimic native cellular microenvironments and enable the growth of any cell type. The low viscosity of the peptide solution means it flows through fine gauge needles easily and is therefore suitable for a range of high accuracy and delicate applications.
Having a reliable and reproducible supply of hydrogels has seen a rise in their use for many cell culture applications. The ability to tailor gel stiffness to match the mechanical properties of a variety of specific tissue types provides an optimal environment to develop more physiologically relevant disease models.
The ability to mimic cell changes using a single material to monitor and recreate the cell changes that occur with age related tissue stiffening allows researchers to effectively model disease progressions and has shown to be particularly beneficial in drug testing, cancer research and tissue and organ regeneration. The ability to carry out controlled testing of drugs on pure samples repeatedly makes the testing of new drugs and treatments a faster and more controlled process.
Choose a Supplier Carefully
Choosing the right company to supply you with synthetic peptide hydrogels is something you should do with care. Opting for a company with extensive experience and one that can tailor material properties to fit precisely to your requirements, including cell therapies, drug delivery and high throughput screening with the precise hydrogel construction, means you will reap all the benefits of these useful hydrogels.
Image Credits: Manchester BIOGEL